We all know that reading and memorizing the Materia Medica is a must for homeopathic practice but how often are we able to do that? Not always! So as to make Materia Medica simple and easily referable Lippe here presents a compiled work on keynotes of homeopathic drugs. It is the author’s masterpiece “Keynotes” adding there to the characteristic symptoms of the most important remedies under the style, “Red line symptoms” gleaned from author’s writings, appearing in several old foreign journals together with the other important ones, collected from the writings of the great Homeopaths of the by- gone days.   In fact, these are the symptoms we need to be abreasted with, to have a successful prescription and hence successful results. The author also puts beyond the red line, the chains of more symptoms leading to correct diagnosis, in a particular characteristic combination. There is also a mention of the modalities and relationship to make our study more complete and easy to analyse. Each sterling symptom has the name of its author indicated against it in abbreviatory form other than Dr. Lippe.